A field experiment was conducted to study the effect of  irrigation and weed management practices of rice under aerobic culture, laid in split plot design. Among the irrigation schedules, IW/CPE ratio of 1.2 produced significantly higher stature of yield attributes, viz., total number of panicles/m2, total number of grains/panicle and number of filled grains/panicle and grain and straw yield were distinctly superior to other two irrigation schedules.  At all the  stages, with exception at 20 DAS, the lowest of density of weeds and  their corresponding dry weight was recorded with hand weeding at 20 and 40 DAS, which were comparable with oxadiargyl 0.07 kg/ha supplemented with HW at 40 DAS for density of grasses, triasulfuron 0.006 kg/ha supplemented with HW at 40 DAS for density of broad leaved weeds and bensulfuron methyl 0.06 kg/ha supplemented with HW at 40 DAS for density of sedges. The highest density of these entire weed categories was recorded with unweeded check. The study revealed that rice can be successfully grown under aerobic culture in north coastal zone of Andhra Pradesh, with pre-emergence application of oxadiargyl 0.07 kg/ha supplemented with HW at 40 DAS for higher productivity.