Some weed species are not controlled by atrazine where the farmers are using this herbicide year after year and different flushes of weeds in rainy season are among the major problems in maize growing areas of India. A field experiment was conducted during the crop growing seasons of 2012 and 2013 at Research Farm, Department of Agronomy, Punjab Agricultural University, Ludhiana to evaluate the efficacy of glyphosate 41% SL against complex weed flora in maize. The treatments included glyphosate 41% SL 900, 1800 and 3600 g/ha applied as post-emergence at 2-4 leaf stage of weeds, atrazine 750 g/ha as pre-emergence, paraquat 24 SL 500 g/ha as post-emergence at 2-4 leaf stage of weeds, 2,4-D sodium salt 1000 g/ha as post-emergence at 2-4 leaf stage of weeds, weed free and unweeded control. The results revealed that non-selective herbicides paraquat at 500 g/ha and glyphosate at 900 and 1800 g/ha as a directed spray in maize as post-emergence at 2-4 leaf stage of weeds recorded effective control of grass and broad-leaf weeds during both the years and recorded grain yield at par with atrazine.