A field experiment was conducted on medium black calcareous clayey soil at Pulses Research Station, Junagadh Agricultural University, Junagadh during three seasons of 2011-12, 2012-13 and 2014-15 to study the efficacy of pre-and post-emergence herbicides in Kharif blackgram (cv. GU-1). The quizalofop-ethyl 40 g/ha as post-emergence (PoE) at 20 days after seeding (DAS) + hand weeding (HW) at 40 days after seeding (DAS) and pendimethalin 900 g/ha as pre-emergence (PE) + hand weeding (HW) at 40 DAS were found equally effective to the weed-free check in controlling weeds and improving growth and yield attributes and ultimately seed yield (1.14 and 1.13 t/ha) and straw yield (1.26 and 1.33 t/ha) of blackgram. These treatments also recorded higher weed control efficiency (65.3 - 63.1%), herbicide efficiency index (81.1 - 82.3%), lower weed index (9.1 - 9.7%) and minimum weed dry biomass (273.9 - 291.7 kg/ha) and higher net returns (Rs. 21,230 and Rs 21,162 /ha). Integrated weed management practices with herbicides as a component were found effective and economical under south Saurashtra agro-climatic conditions of Gujarat.