A field experiment was carried out at G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand during rainy season of 2015 and 2016 to evaluate the efficacy of propanil 80% WG against mixed weed flora in direct-seeded rice. The most dominant weeds were: Echinochloa colona, Echinochloa crus-galli, Leptochloa chinensis, Eleusine indica and Digitaria sanguinalis among grassy weeds; Celosia argentea as broad-leaved weed and Cyperus spp. as sedge. Results revealed that propanil 4000 g/ha being on a par with 3000 g/ha was found most effective for controlling grassy as well as broad-leaved weeds as compared to other herbicidal treatments. The lowest weed biomass (11.9 g/m2) and the highest weed control efficiency (73.6%) were also recorded with this treatment. Propanil 4000 g/ha being on a par with 3000 g/h recorded maximum grain yield (4.6 t/ha) which was superior to rest of the herbicidal treatments.