A field experiment was conducted at Agricultural Research Farm, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi to study effect of nitrogen level and weed management in direct-seeded rice. Treatment consisted of 12 treatment combinations which was laid out in the split-plot design having nitrogen levels (100, 120, 140 and 160 kg N/ha) in main plot and three weed management practices, viz. weedy, two hand weeding and bispyribac-sodium 25g/ha fb Cono-weeding in sub-plots replicated thrice. Two hand weeding recorded significantly lower weed biomass and density and better performance of crop growth and yield attributes and yield followed by bispyribac-Na  25 g/ha fb cono-weeding. In case of nitrogen application of 160 kg N/ha showed better performance of growth, yield attributes and yield as compared to other nitrogen treatments. It was observed that application of nitrogen 160 kg/ha and two hand weeding was found best treatment for higher grain yield and net returns.