A field study was conducted at Dr. Balasdaheb Sawant Konkan Krishi Vidyapeeth, Dapoli (Maharashtra) during Kharif 2011 to 2014 to evaluate the effect of green manuring with Sesbania rostrata and different herbicide on complex weed flora in transplanted rice. The experimental field was infested with Ludwigia octovalis, Cloem viscosa, Cyperus iria, Amaranthus sessils, Isachne globosa and Eriocaulon hexangularis. Four year pooled data revealed that green manuring did not influence the dry matter of monocots and BLWs at all the stages of observation. Green manuring significantly influenced the grain and straw yields of rice and produced significantly higher grain and straw yields (3.86 grain and 3.87 straw t/ha) as compared to without green manuring. Pre-emergence application of pretilachlor-S 0.75 kg/ha at 3-7 DAT recorded the highest weed control efficiency (36.40% at 30 DAT and 48.18% at 50 DAT) and rice grain yield (3.54 t/ha).