Dlapat sagar reservoir is one of the prominent aquatic bodies in Jagdalpur of Bastar region of Chhattisgarh state in India. The reservoir was severely infested by aquatic weeds for last many years. An experiment was done to evaluate the integration of herbicides and manual/mechanical approaches to reduce the cost in comparison to manual removal alone. The experiment comprised of 8 treatments, viz. glyphosate 2.0 and 1.0 kg/ha (41 SL), paraquat 2.0 and 1.0 kg/ha (24 SL) and 2,4-D (amine salt 58% SL) 2.0 and 1.0 kg/ha dissolving in 500 litre water, manual removal and control was laid out in randomized block design with three replications at reservoir located at 1905’41"N and 8200’43"E with elevation of 563 m MSL during 2016 and 2017. The aquatic body was covered with thick mat of different weeds entangled with each other. Herbicides were sprayed to loosen the entangled weed biomass followed by manual and mechanical removal after 25 to 30 days. Glyphostae, 2,4-D and paraquat were mixed with sticker (Latron AG-98) and were sprayed in three replications by power spray machine (1HP HTP MAK ASPEE) mounted on the boat. The pH of water was gradually increased from 6.79 to 7.09 while EC and TDS from 0.33 to 0.30 (mS/cm2) and 101 to 207 (mg/l), respectively. The minimum density and dry matter was recorded with manual/mechanical removal followed by application of glyphosate 2.0 kg/ha, which was significantly superior over control and lower dose of other two herbicides and found statistically at par with 2,4-D amine salt 58% SL and applied at higher dose (2.0 kg/ha) during both the years. Glyphosate (2.0 kg/ha) was found effective in controlling weeds with the cost of ` 19,660/- and ` 18080 per hectare during 2016 and 2017, respectively with weed control efficiency of 86.4, 84.3; 79.1, 82.2 and 83.8, 88.3 % for water hyacinth, lotus and alligator weeds during 2016 and 2017, respectively.