A field experiment was conducted to evaluate the bio-efficacy of dicamba 48% SL on the associated broad-leaf weeds of maize and to assess its phyto-toxicity on the crop in GBPUA&T, Pantnagar for two consecutive years during 2016 and 2017. The results revealed that application of dicamba 48% SL at 300 and 360 g/ha provided superior control of broad-leaved weeds as compared to 2,4-D Amine salt 58% SL 500 g/ha in maize. The same two treatments i.e. dicamba 48% SL at 300 and 360 g/ha also provided a total weed control efficiency of 100% in all the stages of crop growth. Maximum grain yield was recorded in the weed free plots to the tune of 5.45 t/ha and 5.22 t/ha in 2016 and 2017, respectively, which was at par with dicamba 48% SL at 300, 360 and 720 g/ha and the other yield attributing characters followed the same trend in both the years. However, numerically maximum yield was obtained in weed free plots, probably due to effectiveness of dicamba only against the broad-leaf weeds but hand weeding took care of broad spectrum of weeds. It was also revealed that, there were no symptoms of phytotoxicity on maize at any doses of dicamba 48% SL. Hence, it may be concluded that dicamba 48% SL at 300 g/ha was found to be effective against broad-leaved weeds in maize in Pantnagar region of Uttarakhand.