The field was mainly infested with monocot weeds like Echinochloa colona, Dinebra retroflexa and Cyperus iria, whereas dicot weeds Eclipta alba and Alternanthera philoxeroides were less dominant in soybean. The application of quizalofop-p-ethyl 37.5 g/ha + chlorimuron 24 g/ha gave satisfactory control of weeds and it gave highest crop biomass (592 g/m2), seed yield (1.59 t/ha) and net monetary returns (15,918/ha) followed by imazethapyr 75 g/ha which registered the crop biomass (557 g/m2), seed yield (1.52 t/ha) and net monetary returns (14,712/ha). However, 2 hand weedings checked the weed growth and recorded significantly higher seed yield (1.87 t/ha) over rest of the treatments, but net monetary return (15,594/ha) were lower than application of quizalofop-p-ethyl 37.5 g/ha + chlorimuron 24 g/ha.