A field study was carried out during (rainy) Kharif seasons of 2019 and 2020 at Raipur, Chhattisgarh to study the efficacy of eight herbicide treatments in managing weed community dominated by Alternanthera sessilis (L.) R.Br. ex DC. and improving the growth and yield of dry direct-seeded rice. The most dominant weed species was Alternanthera sessilis accounting for 70% of the total weed density in weedy check. Other associated weeds were Echinochloa colona (L.) Link, Brachiaria ramosa (L.) Stapf and Sporobolus diander (Retz.) P. Beauv. among grasses and the sedge Cyperus iria L. The post-emergence of penoxsulam + cyhalofop–butyl 135 g/ha very effectively controlled the A. sessilis and other weeds, produced highest of 5.04 and 4.63 t/ha grain yield and net return of  71409 and 65563/ha and maximum weed control efficiency among the herbicide-based treatments during 2019 and 2020, respectively. Penoxsulam 22.5 g/ha post-emergence and bispyribac-sodium 25 g/ha post-emergence were also found to be equally effective to it with regards to rice grain yield.