A field experiment was conducted on sandy loam soils of Agricultural College Farm, Bapatla, Andhra Pradesh, India, during 2015-16 and 2016-17 in direct-seeded rice (DSR) to test the efficacy of sequential application of herbicides on weed management, rice nutrient uptake and productivity and to assess herbicides residual effect on succeeding greengram. The maximum total nitrogen, phosphorus and potassium uptake at maturity of rice was recorded with pre-emergence application (PE) of bensulfuron-methyl + pretilachlor with safener (ready-mix) at 500 g/ha fb post-emergence application (PoE) of azimsulfuron 20 g/ha at 25 days after seeding (DAS) fb metsulfuron-methyl and chlorimuron-ethyl (ready-mix) 4 g/ha PoE 45 DAS. The soil available nutrient status and the uptake of nitrogen, phosphorus and potassium by succeeding greengram was not influenced by different weed management treatments applied in DSR.