An experiment was conducted at Sardarkrushinagar Dantiwada Agricultural University (SDAU), Sardarkrushinagar, Gujarat during two consecutive winter (Rabi) seasons of the years 2014-15 and 2015-16. The experiment consisted of twenty-one treatments with three levels of irrigation (0.6, 0.8, 1.0 IW:CPE ratio) as main plot treatments and seven weed management practices as sub-plot treatments. A split-plot design with three replications was used. The crop irrigated at 1.0 IW: CPE recorded significantly higher growth parameters, yield attributes, grain and straw yield. Among weed management practices, hand weeding twice and metsulfuron-methyl 4 g/ha at 28 DAS recorded significantly higher yield attributes, grain and straw yield. Interaction between irrigation levels and weed control practices revealed that wheat irrigated at 1.0 IW: CPE in combinations with two hands weeding or metsulfuron-methyl 4 g/ha and clodinafop + metsulfuron-methyl (ready-mix) 60 g/ha produced significantly higher grain yield than other treatments. The economic analysis revealed that irrigation at 1.0 IW:CPE ratio recorded significantly higher net returns of  66188/ha and B:C 2.11. Among weed management treatment, metsulfuron-methyl 4 g/ha) PoE attained maximum net income of  34036/ha with B: C 2.16 and next best was clodinafop + metsulfuron-methyl (ready-mix) 60 g/ha which fetched next highest net income ( 30843/ha) and B:C (2.01).