A field experiment was conducted during the Kharif season of 2011 and 2012 at G.B.Pant University of Agricultureand Technology, Pantnagar to find out the efficacy of bispyribac-sodium in managing weeds in direct-seeded rice. Among the treatments, bispyribac-sodium 20 and 25 g/ha applied at 1-3 leaf stage or at 4-6 leaf stage of the weeds was found the most efficient having lowest weed density and biomass during both the years. Rice grain yield and yield attributing characters (tillers/m2 and grains/panicle) were influenced by the effectiveness of the treatments. The highest grain yield of rice was recorded with weed free (4.03 t/ha) which was at par with bispyribac-sodium 20 and 25 g/ha.