A field experiment was conducted during Rabi seasons (2014-15 and 2015-16) at AICRP-Weed Management, GBPUA&T, Pantnagar, to evaluate the effect of integration of different herbicides and mulching on weeds, yield and economics of garlic. The experiment involved the integration of two mulch treatments in the main plot (with and without rice straw mulch) and four weed management treatments replicated thrice in a split-plot design. The weed density and biomass, weed control efficiency, plant growth parameters and garlic bulb yield varied significantly amongst tested weed management treatments. During both the years, grassy and non-grassy weed density was significantly reduced with rice straw mulch 5 t/ha integration with different herbicides compared to without mulch. The pre-emergence application (PE) of oxyflurofen 0.223 kg/ha recorded lowest density and biomass of all the weeds. The rice straw mulch 5 t/ha resulted in significantly the highest garlic yield (2.95 and 4.25 t/ha); net returns ( 1,75850 and 2,80250/ha and B:C (2.9 and 4.7), during both the years, respectively. Among herbicides, oxyflurofen 0.223 kg/ha PE recorded the highest net returns ( 1,31700 and 2,04100/ha) and B:C (2.4 and 3.7) during both the year, respectively.