An experiment was conducted during three consecutive Kharif seasons of 2021, 2022 and 2023 at Regional Research Station, Anand Agricultural University, Anand, Gujarat, India, to study the effect of weed management practices on weeds and grain yield of dry-seeded rice. The dominant grassy weeds in fields were Echinochloa crus-galli, Echinochloa colona, Leptochloa chinensis and broad-leaf weeds were Digera arvensis, Phyllanthus niruri and Trianthema monogyna on three years pooled basis. Results revealed that, early post emergence application (EPoE) of triafamone 20% + ethoxysulfuron 10% WG (pre-mix) 44.0 + 22.5 g/ha at 10-15 days after sowing (DAS) followed by (fb) hand weeding (HW) at 30 DAS or penoxsulam 1.02% + cyhalofop-butyl 5.1% OD (pre-mix) 120 g/ha at 10-15 DAS fb HW at 30 DAS or pre-emergence application (PE) of pretilachlor 30% + pyrazosulfuron-ethyl 0.75% WG (pre-mix) 600 + 15 g/ha at 1-2 DAS fb HW at 30 DAS or hand weeding 20 and 40 DAS recorded significantly lower density and dry biomass of weeds, higher weed control efficiency, number of tillers, grain yield of rice and B: C. Moreover, there were no any residues of applied herbicides detected in the rice grain and in soil after harvest.