Phalaris minor Retz. now became a problematic weed of wheat in middle Gujarat condition due to its morphological similarity with wheat and continuous use of broad-spectrum herbicide. To combat this problem, an experiment was conducted during winter (Rabi) season of  2021-22 and 2022-23 on loamy sand soil at the farm of AICRP-Weed Management, Anand Agricultural University (Gujarat). The study aimed to find out instead of studied effect of herbicides against P. minor and other weeds in wheat. Results revealed that pre-mix (PM) application of clodinafop-propargyl 15% + metsulfuron-methyl 1% WP (PM) 60 + 4 g/ha as post-emergence (PoE) or sulfosulfuron 75% + metsulfuron-methyl 5% WG (PM) 30 + 2 g/ha PoE and sequential application of pendimethalin 30% EC 500 g/ha as pre-emergence (PE) fb clodinafop-propargyl 15% WP 60 g/ha PoE or sulfosulfuron 75% WP 30 g/ha PoE or hand weeding at 20 and 40 days after sowing (DAS) provide effective control of P. minor with broad-spectrum weed control resulted in higher grain yield and benefit-cost ratio.