Broad spectrum post-emergence herbicides are being popular among the chickpea growers. However, systematic study is required to assess the effectiveness of these in comparison with popular pre-emergence herbicides and hence a field study was conducted at Indira Gandhi Krishi Vishwavidyalaya, Raipur in Alfisols during winter (Rabi) season of 2020-21 and 2021-22 to study the effect of pre-emergence and combination of pre- and post-emergence herbicides in chickpea (Cicer arietinum L.) with mechanical/hand weeding. The experiment was designed in randomized block design with three replications. Major weeds were Chenopodium album and Cichorium intybus. Echinochloa colona, Cynadon dactylon with almost 50% dominance of Medicago denticulata. Among the chemical weed management treatments, the lowest count of the aforesaid individual and total weeds was registered under the treatment topramezone 25.28 g/ha as POST at 90 DAS. Topramezone 25.28 g/ha as PoE (18 DAS) reduced total weed density by 50% at 90 DAS when compared with weedy check and eventually had higher weed control efficiency in both the years (81.1 in 2020-21 and 83.8% in 2021-22) than the other treatments. Comparable lower weed count was also observed under the hand weeding at 30 DAS/Farmers practice. Although, slight phytotoxicity (3 to 5 out of 10 scale) in terms of yellowing, stunting and scorching was observed upto 14 days in topramezone 25.28 g/ha as PoE, propaquizafop+ imazethapyr 125 g/ha as POST and flauzifop-p-butyl + fomesafen 250 g/ha PoE, but these symptoms were entirely disappeared and chickpea has recovered and regained its growth later. Application of topramezone produced average 275% more seed yield over weedy check and 133% over  pendimethalin 678 g/ha PE. It also generated the highest net return (Rs. 53290 and 54630/ha) and B:C ratio (3.35 and 3.33).