To find out the effect of different methods of herbicide application in garlic, a study was carried out during rabi season of 2006 at CCS Haryana Agricultural University, Hisar. Percent control of weeds was not affected due to method of application of herbicides. Pre-emergence application of pendimethalin at 1.0 kg/ha, oxyfluorfen at 200 and 250 g/ha, pre-emergence spray of trifluralin at 1.0 kg/ha either through sand mixing or spray and oxadiargyl at 100 g/ha applied as pre emergence or 10 and 25 days after transplanting (DAT) as post emergence spray supplemented with one hoeing proved very effective in minimizing population of C. album, Melilotus indica and Coronopus didymus. Efficacy of early post emergence application of oxadiargyl was more as compared to its pre emergence application.