Pinoxaden was evaluated for the control of grass weeds in wheat and barley. It was very effective in controlling Phalaris minor Retz., Avena ludoviciana Dur. and Polypogon monspeliensis (L.) Desf., but was ineffective in controlling broad-leaved weeds. The efficacy of pinoxaden without surfactant was significantly inferior to surfactant application. In various experiments, pinoxaden with surfactant improved the wheat yield >68% over control. The efficacy of pinoxaden (35 g/ha) in controlling grass weeds in wheat was similar to that of clodinafop 60 g/ha, fenoxaprop 100 g/ha and sulfosulfuron 25 g/ha. Wheat yields among these herbicides were similar, where fields were having dominance of grass weeds, but in the presence of both grassy and broad-leaved weeds, sulfosulfuron had an edge over three grass herbicides (pinoxaden, fenoxaprop and clodinafop) tested. Toxicity was not observed on any of the 18 barley genotypes screened for their sensitivity to pinoxaden (30 and 60 g/ha). Pinoxaden @ 30 g/ha effectively controlled isoproturon resistant P. minor in barley and provided 21.6% higher yield compared to isoproturon application.