Experiment to evaluate the bioefficacy of pinoxaden 5 EC in combination with carfentrazone in wheat was conducted in sandy loam soil at CCS HAU Hisar during Rabi seasons of 2008-09 and 2009-10, at Agronomy Research Area of CCS Haryana Agricultural University, Hisar. The dominant weeds present in experimental field were little seed canary grass (Phalaris minor Retz.) among grassy weeds and Chenopodium album, Convolvulus arvensis and Melilotus indica among broadleaf weeds. Use of carfentrazone 25 g/ha at 35 DAS and pinoxaden 40 g/ha 7 days after carfentrazone use was not as effective against P.minor as pinoxaden use at 35 days after sowing. Post-emergence use of pinoxaden at 50 g/ha (35 DAS) with sequential use carfentrazone at 25 g/ha (42 DAS) with 1% ammonium sulphate provided complete control grassy and broadleaf weeds without any phytotoxic effect on wheat crop.