Field experiment was conducted during Kharif 2009 and 2010 to study the effect of rice seed rate (20, 30, 40 and 50 kg/ha) and inter row spacing (15, 20, 25 and 30 cm) on weeds, crop growth and grain yield of direct-seeded rice. Population of Echinochloa and Cyperus was minimum when DSR was sown with seed rate of 50 kg/ha with 15-20 cm row spacing and it was maximum when lower seed rate of 20-30 kg/ha was used with wider row spacing of 30 cm. Weed biomass was significantly affected by seed rate, being maximum with lower seed rate usage of 20 kg/ha and decreased significantly with each successive increase in seed rate. With the increase in row spacing from 15 to 30 cm, weed biomass increased significantly.  Maximum number of tillers was recorded when rice was sown with seed rate of 50 kg/ha with wider row spacing of 30 cm. The seed rates and row spacings did not have any significant effect on effective tillers and grain yield of dry-drilled rice.