Effect of rice establishment methods and weed management practices on weeds and grain yield of rice was studied. The maximum reduction of weed species was obtained with application of herbicides as pre-emergence supplemented by two hand weedings at 30 and 60 days after seeding/days after transplanting under all the establishment systems of rice. The maximum weed dry matter reduction was achieved due to herbicide supplemented with two hand weedings in transplanted rice followed by herbicide as pre-emergence supplemented with two hand weedings in wet seeded rice and zero till rice. The highest grain yield (4623 kg ha") was achieved by the application of herbicide supplemented with two hand weedings in transplanted rice which was significantly higher than the other treatments. Among the direct seeded rice, the highest yield (4222 kg ha') .was recorded under wet seeding (WSR) employed with two hand weedings (We. - two hand weedings) and on par with application of herbicide followed by one hand weeding (We,) ullder transplanting (TPR).