A field experiment was carried out at Pantnagar during Rabi season of 2010-11 and 2011-12 to test the efficacy of different doses of metribuzin 42% + clodinafop-propargyl 12% WG in wheat and associated weeds. The soil of the experimental field was clay loam in texture, medium in organic carbon (0.67%), available phosphorus (29.6 kg/ha) and potassium (176.4 kg/ha) with pH 7.2. Results revealed that metribuzin + clodinafop-propargyl 500 g/ha was significantly at par with its higher dose at 600g/ha, and two hand weedings at 30 and 50 DAS recorded the lowest density of Phalaris minor and Chenopodium album, Coronopus didymus, Melilotus spp., Rumex spp. and Fumaria parviflora at 30 and 60 days after application as compared to rest of the treatments. Maximum grain yield was recorded in metribuzin 42%+ clodinafop-propargyl at 600 g/ha, which was statistically at par with its lower dose of 500 g/ha due to effective control of grassy and broad-leaf weeds in wheat.