A field experiment was conducted during 2008-09 and 2009-10 at the Agricultural Research Farm of C.C.R. (P.G.) College Muzaffarnagar (U.P.) to study the integration of chemical and cultural weed management practices in spring planted sugarcane. The experiment consisted of ten treatments laid out in randomized block design with three replications. Cyperus rotundus, Cynodon dactylon and Sorghum halepense were observed as major weeds in both the year. All the weed management practices led to significant reduction in density and dry matter of weeds when compared to weedy check. Hoeing done at 30, 60, 90 DAP recorded lowest weed density (23.77 and 22.07/m2) and dry matter (8.71 and 8.34 g/m2) with mean WCE of 57.0% and was found at par with the application of glyphosate 1.0 kg/ha as pre-emergence + atrazine 2.0 kg/ha after 1st irrigation + one hoeing at 90 DAP (density 24.14 and 23.29/m2, dry matter 10.99 and 10.61 g/m2 and WCE 45.5%). The mean reduction in cane yield ranged from 39.0% under weedyconditions to 8.0% with the crop received 03 hoeing at 30, 60 and 90 DAP and it was closely followed by the glyphosate 1.0 kg/ha as pre-emergence + atrazine 2.0 kg/ha after 1st irrigation + one hoeing at 90 DAP and atrazine 2.0 kg/ha as pre-emergence + one hoeing at 60 DAP. Further, the cane yield was recorded highest (88.8 t/ha) when crop raised with 3 hoeing at 30, 60, 90 DAP which was closely followed (87.9 t/ ha) by glyphosate 1.0 kg/ha as pre- emergence + atrazine 2.0 kg/ha after 1st irrigation + one hoeing at 90 DAP.