A field experiment was conducted during 2012-13, to study the effect of herbicides applied in mixture and sequence for managing complex weed flora in transplanted rice. Among the herbicides applied, bispyribac-Na applied in combination with almix as tank mixture recorded the least weed count, weed dry matter and highest WCE. Significantly higher yield attributes, viz. number of grains/panicle and grain yield were also recorded when bispyribac-Na and metsulfuron-methyl + chlorimuron-ethyl were applied as tank mixture. Pre-emergence application of pretilachlor fb post-emergence application of metsulfuron-methyl + chlorimuron-ethyl and hand weeding twice at 25 and 45 DAT were also equally effective. Application of pre- and post-emergence herbicide alone were found to be less effective in reducing weed density and weed dry matter.