The field was infested with monocot weeds like Echinochloa colona, Cyperus iria whereas dicot weeds Alternanthera philoxiroides, Eclipta alba, Commelina benghalensis and Phyllanthus niruri were less dominant in soybean. The application of Chlorimuron-ethyl 24 g/ha as early post-emergence along with mechanical weeding was most effective in paralyzing the weed growth to that of chlorimuron-ethyl (12, 24, 36, 48 and 72 g/ha) and mechanical weeding at 20 DAS. The application of chlorimuron-ethyl herbicide at 24 g/ha as early post-emergence along with mechanical weeding was significant superior for growth parameters, yield attributes and seed yield (1.61 t/ha) of soybean than rest of the treatments without any phytotoxicity on soybean plants and was found more remunerative in terms of NMR (Rs  20023.8) and B-C ratio (2.06) than application of chlorimuron-ethyl herbicide at 12 g/ha to 72 g/ha, as early post-emergence. Two hand weedings (20 and 40 DAS) proved to be the best in terms of yield (1.69 t/ha grain, 3.49 t/ha stover); however, NMR (Rs 20011.7/ha) was almost at par to chlorimuron 24 g along with mechanical weeding (Rs 20023.8/ha).